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Unité de Formation et de Recherche de Chimie
UFR926

"Creating New (Bioactive) Molecules with Superacids" on Monday January 28th 2019

Sébastien THIBAUDEAU

(IC2MP Poitiers University)

sebastien.thibaudeau @ univ-poitiers.fr

 

Creating New (Bioactive) Molecules with Superacids

 

Abstract:

 

In superacid, such as HF/SbF5, functionalized organic molecules can be

(poly)protonated to furnish electrophilic species which can react with very poornucleophiles. This superelectrophilic activation can be applied to the development of unprecedented organic reactions. This work opens new possibilities for the direct and effective preparation ofelaborated compounds of high synthetic and biologicalvalues

12/03/19

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